Cov ntaub ntawv dav dav
Interleukin-6 (IL-6) yog ib qho multifunctional α-helical cytokine uas tswj kev loj hlob ntawm tes thiab kev sib txawv ntawm ntau cov ntaub so ntswg, uas paub tshwj xeeb tshaj yog rau nws lub luag haujlwm hauv kev tiv thaiv kab mob thiab kev mob hnyav.IL-6 protein yog secreted los ntawm ntau hom cell xws li T hlwb thiab macrophages ua phosphorylated thiab variably glycosylated molecule.Nws ua haujlwm los ntawm nws cov heterodimeric receptor uas muaj IL-6R uas tsis muaj tyrosine / kinase domain thiab khi IL-6 nrog qis affinity, thiab ubiquitously qhia glycoprotein 130 (gp130) uas khi IL-6.IL-6R complex nrog siab affinity thiab yog li transduces teeb liab.IL-6 kuj tseem koom nrog hauv hematopoiesis, cov pob txha metabolism, thiab kev mob qog noj ntshav, thiab tau raug txhais tias yog lub luag haujlwm tseem ceeb hauv kev coj mus rau kev hloov pauv hauv lub cev mus rau kev tiv thaiv kab mob.
Pair pom zoo | CLIA (Capture-Detection): 1B1-4 ~ 2E4-1 2E4-1 ~ 1B1-4 |
Purity | > 95%, txiav txim los ntawm SDS-PAGE |
Buffer Formulation | PBS, pH 7.4. |
Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20 ℃ to -80 ℃ thaum tau txais. Pom zoo kom aliquot cov protein rau hauv me me kom pom kev cia. |
Khoom npe | Cat.Tsis muaj | Clone ID |
IL6 | AB 0001-1 | 1B1-4 |
AB 0001-2 | 2 E4-1 | |
AB 0001-3 | 2 C3-1 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
1.Zhong Z , Darnell ZW , Jr. Stat3: ib tsev neeg STAT qhib los ntawm tyrosine phosphorylation nyob rau hauv teb rau epidermal loj hlob yam thiab interleukin-6 [J].Science, 1994.
2.J, Bauer, F, et al.Interleukin-6 hauv kev kho mob tshuaj [J].Annals ntawm Hematology, 1991.