Anti-tib neeg GDF15 Antibody, Mouse Monoclonal
Cov ntsiab lus ntawm cov khoom
Cov ntaub ntawv dav dav
Growth-differentiation factor 15 (GDF15), tseem hu ua MIC-1, yog tus tswvcuab zais cia ntawm qhov hloov pauv kev loj hlob (TGF)-β superfamily, raws li cov tshuaj tiv thaiv kev tiv thaiv kab mob tshiab hauv lub plawv.GDF-15 / GDF15 tsis qhia nyob rau hauv ib txwm neeg laus lub plawv tab sis yog induced nyob rau hauv cov lus teb rau tej yam kev mob uas txhawb hypertrophy thiab dilated cardiomyopathy thiab nws yog heev nthuav nyob rau hauv daim siab.GDF-15 / GDF15 muaj lub luag haujlwm hauv kev tswj cov kab mob inflammatory thiab apoptotic hauv cov ntaub so ntswg raug mob thiab thaum muaj kab mob.GDF-15 / GDF15 yog synthesized li precursor molecules uas tau ua nyob rau hauv ib tug dibasic cleavage site tso tawm C-terminal domains uas muaj ib tug yam ntxwv motif ntawm 7 conserved cysteine nyob rau hauv lub mature protein.GDF-15 / GDF15 overexpression tshwm sim los ntawm qhov nthuav dav erythroid compartment pab txhawb cov hlau overload hauv thalassemia syndromes los ntawm inhibiting hepcidin qhia.
Cov khoom
| Pair pom zoo | CLIA (Capture-Detection): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
| Purity | > 95%, txiav txim los ntawm SDS-PAGE |
| Buffer Formulation | PBS, pH 7.4. |
| Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20 ℃ to -80 ℃ thaum tau txais. Pom zoo kom aliquot cov protein rau hauv me me kom pom kev cia. |
Kev sib piv
Cov ntaub ntawv xaj
| Khoom npe | Cat.Tsis muaj | Clone ID |
| GDF-15 | AB 0038-1 | 3 A2-1 |
| AB 0038-2 | 23 F1-5 | |
| AB 0038-3 | 6 C1-9 | |
| AB 0038-4 | 4D5-8 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
Citations
1.Wolert KC, Kempf T, Peter T, et al.Prognostic Value of Growth-Differentiation Factor-15 in Patients With Non-ST-Elevation Acute Coronary Syndrome[J].Circulation, 2007, 115(8): 962-971.
2.Kempf T, Haehling SV, Peter T, et al.Prognostic utility of growth differentiation factor-15 nyob rau hauv cov neeg mob uas mob plawv tsis ua hauj lwm.[J].Phau ntawv Journal of the American College of Cardiology, 2007, 50(11): 1054-1060.
