Anti- human CHI3L1 Antibody, human Monoclonal
Cov ntsiab lus ntawm cov khoom
Cov ntaub ntawv dav dav
Chitinase-3-zoo li protein 1 (CHI3L1) yog ib qho secreted heparin-binding glycoprotein uas nws qhia tau txuam nrog vascular du nqaij cell migration.CHI3L1 tau qhia nyob rau theem siab hauv cov kab lis kev cai tom qab nodular VSMC thiab nyob rau theem qis hauv cov kab lis kev cai subconfluent proliferating.CHI3L1 yog cov ntaub so ntswg txwv, chitin-binding lectin thiab cov tswv cuab ntawm glycosyl hydrolase tsev neeg 18. Hauv kev sib piv rau ntau lwm cov cim monocyto / macrophage, nws cov lus qhia tsis muaj nyob hauv monocytes thiab muaj zog induced thaum lub sij hawm lig theem ntawm tib neeg macrophage sib txawv.Kev nce qib ntawm CHI3L1 yog txuam nrog cov teeb meem uas nthuav tawm cov ntaub so ntswg sib txuas ntxiv, xws li rheum atoid, mob caj dab, osteoarthritis, scleroderma, thiab cirrhosis ntawm daim siab, tab sis yog tsim los ntawm pob txha mos los ntawm cov laus pub dawb los yog cov neeg mob osteoarthritis.CHI3L1 yog qhov txawv txav hauv hippocampus ntawm cov neeg mob uas muaj tus mob schizophrenia thiab tuaj yeem koom nrog hauv cov lus teb ntawm tes rau ntau yam xwm txheej ib puag ncig uas tau tshaj tawm tias yuav ua rau muaj kev pheej hmoo ntawm tus mob schizophrenia.
Cov khoom
| Pair pom zoo | CLIA (Capture-Detection): 2E4-2 ~ 1G11-14 13F3-1 ~ 1G11-14 |
| Purity | > 95%, txiav txim los ntawm SDS-PAGE |
| Buffer Formulation | PBS, pH 7.4 |
| Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20 ℃ to -80 ℃ thaum tau txais. Rau lub sijhawm ntev cia, thov aliquot thiab khaws cia.Tsis txhob rov khov thiab thawing cycles. |
Sib piv Analysis
| Bioantibody | kho mob kuaj mob | Tag nrho | |
| zoo | Tsis zoo | ||
| zoo | 46 | 3 | 49 |
| Tsis zoo | 4 | 97 | 101 |
| Tag nrho | 50 | 100 | 150 |
| kev ntsuas ntsuas | rhiab heev | tshwj xeeb | raug |
| 92% | 97% | 95% | |
Cov ntaub ntawv xaj
| Khoom npe | Cat.Tsis muaj | Clone ID |
| CHI3L1 | AB 0031-1 | 1 G11-14 |
| AB 0031-2 | 2 E4-2 | |
| AB 0031-3 | 3 A12-1 | |
| AB 0031-4 | 13 F3-1 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
Citations
1.Kyrgios I, Galli-Tsinopoulou A, Stylianou C, et al.Kev nce qib ntawm cov ntshav qab zib theem protein ntau YKL-40 (chitinase 3-zoo li protein 1) yog cov cim ntawm kev rog thiab insulin tsis kam hauv cov menyuam yaus prepubertal [J].Metabolism-clinical & Experimental, 2012, 61(4): 562-568.
2.Yu-Huan M, Li Ming T, Jian-Ying LI, et al.Kev ntsuam xyuas ntawm daim ntawv thov ntawm serum chitinase-3-zoo li protein 1, alpha-fetoprotein thiab ferritin nrhiav kom paub kuaj mob hepatocellular carcinoma [J].Kev Tiv Thaiv Tshuaj Tiv Thaiv, 2018.
