Anti-tib neeg AFP Antibody, Mouse Monoclonal
Cov ntsiab lus ntawm cov khoom
Cov ntaub ntawv dav dav
Alpha-fetoprotein (AFP) yog cais raws li ib tug tswv cuab ntawm albuminoid noob superfamily muaj albumin, AFP, vitamin D (Gc) protein, thiab alpha-albumin.AFP yog glycoprotein ntawm 591 amino acids thiab carbohydrate moiety.AFP yog ib qho ntawm ob peb lub embryo-specific proteins thiab yog ib qho tseem ceeb ntawm cov protein nyob rau hauv tib neeg lub embryonic lub neej raws li ib lub hlis, thaum albumin thiab transferrin muaj nyob rau hauv kuj me me.Nws yog thawj synthesized nyob rau hauv tib neeg los ntawm lub yolk sac thiab daim siab (1-2 lub hlis) thiab tom qab feem ntau nyob rau hauv daim siab.Ib qho me me ntawm AFP yog tsim los ntawm GI ib puag ncig ntawm tib neeg lub tswv yim.Nws tau raug pov thawj tias AFP tuaj yeem rov tshwm sim hauv cov ntshav hauv cov ntshav nce siab hauv cov neeg laus lub neej hauv kev koom nrog cov txheej txheem kho dua qub thiab nrog kev loj hlob tsis zoo.Alpha-fetoprotein (AFP) yog ib qho cim tshwj xeeb rau hepatocellular carcinoma (HCC), teratoblastomas, thiab neural tube defect (NTD).
Cov khoom
| Pair pom zoo | CLIA (Capture-Detection): 3C8-6 ~ 11D1-2 8A3-7 ~ 11D1-2 |
| Purity | > 95%, txiav txim los ntawm SDS-PAGE |
| Buffer Formulation | PBS, pH 7.4. |
| Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20℃rau -80℃thaum tau txais. Pom zoo kom aliquot cov protein rau hauv me me kom pom kev cia. |
Sib piv Analysis
Cov ntaub ntawv xaj
| Khoom npe | Cat.Tsis muaj | Clone ID |
| AFP | AB 0069-1 | 11 D1-2 |
| AB 0069-2 | 3 C8-6 | |
| AB 0069-3 | 8 A3-7 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
Citations
1.Mizejewski GJ.(2001) Alpha-fetoprotein Structure and Function: Relevance to Isoforms, Epitopes, and Conformational Variants.Exp Biol Med.226(5): 377-408.
2.Tomasi TB, et al.(1977) Cov Qauv thiab Kev Ua Haujlwm ntawm Alpha-Fetoprotein.Kev tshuaj xyuas txhua xyoo ntawm Tshuaj.28:453-65.
3.Leguy MC, et al.(2011) Kev ntsuam xyuas ntawm AFP hauv cov kua dej amniotic: kev sib piv ntawm peb txoj kev siv tshuab.Ann Biol Clin.69(4): 441-6.
