Anti-tib neeg SHBG Antibody, Mouse Monoclonal
Cov ntsiab lus ntawm cov khoom
Cov ntaub ntawv dav dav
Kev sib deev hormone binding globulin (SHBG) yog glycoprotein txog 80-100 kDa;nws muaj affinity siab rau 17 beta-hydroxysteroid cov tshuaj hormones xws li testosterone thiab estradiol.SHBG
Cov concentration hauv plasma yog tswj hwm los ntawm, ntawm lwm yam, androgen / estrogen tshuav, thyroid hormones, insulin thiab noj zaub mov.Nws yog qhov tseem ceeb tshaj plaws thauj protein rau estrogens thiab androgens hauv cov ntshav peripheral.SHBG concentration yog ib qho tseem ceeb uas tswj lawv cov kev faib tawm ntawm cov protein-bound thiab dawb xeev.Plasma SHBG concentrations yog
cuam tshuam los ntawm ntau yam kab mob sib txawv, qhov muaj txiaj ntsig siab tau pom nyob rau hauv hyperthyroidism, hypogonadism, androgen insensitivity thiab siab cirrhosis hauv cov txiv neej.Tsawg concentrations muaj nyob rau hauv myxoedema, hyperprolactinaemia thiab cov tsos mob ntawm kev ua haujlwm androgen ntau dhau.Kev ntsuas ntawm SHBG yog qhov muaj txiaj ntsig zoo hauv kev ntsuam xyuas qhov mob me me ntawm androgen metabolism thiab ua kom pom cov poj niam uas muaj hirsutism uas muaj feem cuam tshuam rau kev kho tshuaj estrogen.
Cov khoom
| Pair pom zoo | CLIA (Capture-Detection): 3E10-1 ~ 3A10-5 3A10-5 ~ 3D8-2 |
| Purity | > 95%, txiav txim los ntawm SDS-PAGE |
| Buffer Formulation | PBS, pH 7.4. |
| Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20 ℃ to -80 ℃ thaum tau txais. Pom zoo kom aliquot cov protein rau hauv me me kom pom kev cia. |
Kev sib piv
Cov ntaub ntawv xaj
| Khoom npe | Cat.Tsis muaj | Clone ID |
| SHBG | AB 0030-1 | 3 A10-5 |
| AB 0030-2 | 3 E10-1 | |
| AB 0030-3 | 3D 8-2 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
Citations
1. Selby C. Kev sib deev hormone binding globulin: keeb kwm, kev ua haujlwm thiab qhov tseem ceeb ntawm kev kho mob.Ann Clin Biochem 1990; 27:532-541.
2. Pugeat M, Crave JC, Tourniare J, et al.Clinical utility ntawm kev sib deev hormone binding globulin ntsuas.Horm Res 1996; 45(3-5): 148-155.
