Anti-tib neeg RBP4 Antibody, Mouse Monoclonal
Cov ntsiab lus ntawm cov khoom
Cov ntaub ntawv dav dav
Retinol-binding protein 4 (RBP4) yog cov neeg nqa khoom tshwj xeeb rau retinol (tseem hu ua vitamin A), thiab yog lub luag haujlwm rau kev hloov pauv ntawm cov retinol tsis ruaj khov thiab insoluble hauv cov kua dej rau hauv cov kua dej kom ruaj khov thiab soluble hauv cov ntshav los ntawm lawv cov kev sib tshuam nruj.Raws li ib tug tswv cuab ntawm lipocalin superfamily, RBP4 uas muaj cov qauv β-chim nrog cov kab noj hniav zoo tau tso tawm los ntawm daim siab, thiab tom qab ntawd xa cov retinol los ntawm daim siab khw muag khoom mus rau cov ntaub so ntswg peripheral.Hauv plasma, RBP4-retinol complex cuam tshuam nrog transthyretin (TTR), thiab qhov kev khi no tseem ceeb heev rau kev tiv thaiv RBP4 excretion los ntawm lub raum glomeruli.RBP4 qhia los ntawm qhov chaw ectopic zoo xa cov retinol rau lub qhov muag, thiab nws qhov tsis txaus cuam tshuam rau qhov pom kev hmo ntuj loj.Tsis ntev los no, RBP4 raws li ib qho adipokine, pom tau hais tawm hauv cov ntaub so ntswg adipose thiab cuam tshuam nrog kev rog, insulin tsis kam (IR) thiab hom 2 mob ntshav qab zib (T2DM).
Cov khoom
| Pair pom zoo | CLIA (Capture-Detection): 9D11-8 ~ 3D4-1 3C8-1 ~ 3D4-1 |
| Purity | > 95% raws li kev txiav txim los ntawm SDS-PAGE. |
| Buffer Formulation | PBS, pH 7.4. |
| Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20 ℃ to -80 ℃ thaum tau txais. Pom zoo kom aliquot cov protein rau hauv me me kom pom kev cia. |
Kev sib piv
Cov ntaub ntawv xaj
| Khoom npe | Cat.Tsis muaj | Clone ID |
| RBP4 | AB 0032-1 | 9D11-8 |
| AB 0032-2 | 3 C8-1 | |
| AB 0032-3 | 3D4-1 | |
| AB 0032-4 | 1 C6-1 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
Citations
1.Aiwei YB, Vijayalakshmi V, Bodles AM, et al.Retinol binding protein 4 qhia hauv tib neeg: kev sib raug zoo rau insulin tsis kam, o, thiab teb rau pioglitazone.[J].J Clin Endocrinol Metab (7): 2590-2597.
2. Haider DG, Karin S, Gerhard P, et al.Serum retinol-binding protein 4 yog txo tom qab poob phaus hauv morbidly rog rog.[J].Phau ntawv Journal of Clinical Endocrinology & Metabolism (3): 1168-71.
