Anti-tib neeg PLGF Antibody, Mouse Monoclonal
Cov ntsiab lus ntawm cov khoom
Cov ntaub ntawv dav dav
Preeclampsia (PE) yog ib qho teeb meem loj ntawm cev xeeb tub uas muaj ntshav siab thiab proteinuria tom qab 20 lub lis piam ntawm cev xeeb tub.Preeclampsia tshwm sim nyob rau hauv 3-5% ntawm cev xeeb tub thiab ua rau muaj ntau yam niam thiab fetal los yog neonatal morbidity thiab morbidity.Kev kho mob tshwm sim tuaj yeem sib txawv ntawm cov ntawv me mus rau qhov hnyav;preeclampsia tseem yog ib qho ntawm cov ua rau fetal thiab leej niam morbidity thiab tuag.
Preeclampsia zoo li yog vim qhov tso tawm ntawm cov yam ntxwv angiogenic los ntawm cov placenta uas ua rau endothelial tsis ua haujlwm.Cov qib ntshav ntawm PlGF (placental growth factor) thiab sFlt-1 (soluble fms-zoo li tyrosine kinase-1, tseem hu ua soluble VEGF receptor-1) tau hloov pauv hauv cov poj niam uas muaj preeclampsia.Ntxiv mus, cov theem ntawm PlGF thiab sFlt-1 tuaj yeem cuam tshuam kev xeeb tub los ntawm preeclampsia txawm tias ua ntej cov tsos mob tshwm sim.Nyob rau hauv ib txwm cev xeeb tub, qhov pro-angiogenic yam PlGF nce thaum thawj ob peb lub hlis twg thiab txo qis thaum cev xeeb tub mus rau lub sijhawm.Hauv qhov sib piv, qib ntawm cov tshuaj tiv thaiv angiogenic sFlt-1 nyob ruaj khov thaum lub sijhawm ntxov thiab nruab nrab ntawm cev xeeb tub thiab nce tsis tu ncua mus txog rau lub sijhawm.Hauv cov poj niam uas muaj tus kab mob preeclampsia, sFlt-1 qib tau pom tias siab dua thiab PlGF qib tau pom tias qis dua thaum cev xeeb tub.
Cov khoom
| Pair pom zoo | CLIA (Capture-Detection): 7G1-2 ~ 5D9-3 5D9-3 ~ 7G1-2 |
| Purity | > 95% raws li kev txiav txim los ntawm SDS-PAGE. |
| Buffer Formulation | PBS, pH 7.4. |
| Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20 ℃ to -80 ℃ thaum tau txais. Pom zoo kom aliquot cov protein rau hauv me me kom pom kev cia. |
Kev sib piv
Cov ntaub ntawv xaj
| Khoom npe | Cat.Tsis muaj | Clone ID |
| PLGF | AB 0036-1 | 7 G1-2 |
| AB 0036-2 | 5D9-3 | |
| AB 0036-3 | 5 G7-1 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
Citations
1.Brown MA, Lindheimer MD, de Swiet M, et al.Kev faib tawm thiab kev kuaj mob ntawm kev mob ntshav siab ntawm cev xeeb tub: nqe lus los ntawm International Society for the Study of Hypertension in Pregnancy (ISSHP).Hypertens Pregnancy 2001; 20(1): IX-XIV.
2.Uzan J, Carbonnel M, Piconne O, et al.Pre-eclampsia: pathophysiology, kuaj mob, thiab tswj.Vasc Health Risk Manag 2011; 7:467-474.
