Anti- human PIVKA-II Antibody, Mouse Monoclonal
Cov ntsiab lus ntawm cov khoom
Cov ntaub ntawv dav dav
Protein Induced by Vitamin K Absence los yog Antagonist-II (PIVKA-II), los yog Des-γ-carboxy-prothrombin (DCP), yog ib qho txawv txav ntawm prothrombin.Nquag, prothrombin's 10 glutamic acid residues (Glu) hauv γ-carboxyglutamic acid (Gla) domain ntawm txoj haujlwm 6, 7, 14, 16, 19, 20,25, 26, 29 thiab 32 yog γ-carboxylated rau Gla -K nyob ntawm γ- glutamyl carboxylase hauv daim siab thiab tom qab ntawd tso rau hauv cov ntshav.Hauv cov neeg mob uas muaj kab mob hepatocellular carcinoma (HCC), γ-carboxylation ntawm prothrombin yog qhov tsis zoo kom PIVKA-II yog tsim los ntawm prothrombin.PIVKA-II yog suav hais tias yog ib qho txiaj ntsig biomarker tshwj xeeb rau HCC.
Cov khoom
| Pair pom zoo | CLIA (Capture-Detection): 1E5-1 ~ 1D6-10 1E5-1 ~ 1E6-7 |
| Purity | > 95%, txiav txim los ntawm SDS-PAGE |
| Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH 7.4 |
| Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20 ℃ to -80 ℃ thaum tau txais. Rau lub sijhawm ntev cia, thov aliquot thiab khaws cia.Tsis txhob rov khov thiab thawing cycles. |
Sib piv Analysis
Cov ntaub ntawv xaj
| Khoom npe | Cat.Tsis muaj | Clone ID |
| PIVKA-Ⅱ | AB 0009-1 | 1 F4-5 |
| AB 0009-2 | 1 E5-1 | |
| AB 0009-3 | 1D6-10 | |
| AB 0009-4 | 1 E6-7 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
Citations
1. Matsueda K, Yamamoto H, Yoshida Y, et al.Hepatoid carcinoma ntawm pancreas tsim cov protein tshwm sim los ntawm qhov tsis muaj vitamin K lossis antagonist II (PIVKA-II) thiab α-fetoprotein (AFP) [J].Phau ntawv Journal of Gastroenterology, 2006, 41(10): 1011-1019.
2.Viggiani, Valentina, Palombi, 等.Protein induced los ntawm vitamin K tsis muaj los yog antagonist-II (PIVKA-II) tshwj xeeb nce nyob rau hauv Italian hepatocellular carcinoma cov neeg mob.[J].Scandinavian Journal of Gastroenterology, 2016.
3.Simundic AM.Cov tswv yim pom zoo rau kev txheeb xyuas kev txheeb cais thiab cov ntaub ntawv nthuav tawm hauv Biochemia Medica phau ntawv journal [J].Biochemia Medica, 2012, 22(1).
4. Tartaglione S, Pecorella I, Zarrillo SR, et al.Protein Induced by Vitamin K Absence II (PIVKA-II) raws li ib tug muaj peev xwm serological biomarker nyob rau hauv pancreatic cancer: ib tug pilot kawm [J].Biochemia Medica, 2019, 29(2).
