Cov ntaub ntawv dav dav
IGFBP1, tseem hu ua IGFBP-1 thiab insulin-zoo li kev loj hlob zoo-binding protein 1, yog ib tug tswv cuab ntawm insulin-zoo li kev loj hlob yam-binding protein tsev neeg.IGF binding proteins (IGFBPs) yog cov proteins ntawm 24 txog 45 kDa.Tag nrho rau IGFBPs sib koom 50% homology thiab muaj kev sib koom ua ke rau IGF-I thiab IGF-II ntawm tib qhov kev txiav txim siab ntau npaum li cov ligands muaj rau IGF-IR.IGF-binding proteins ncua ib nrab-lub neej ntawm IGFs thiab tau pom tias yog inhibit los yog txhawb kev loj hlob-txhim kho cov teebmeem ntawm IGFs ntawm cell culture.Lawv hloov pauv kev sib cuam tshuam ntawm IGFs nrog lawv cov cell nto receptors.IGFBP1 muaj IGFBP sau thiab thyroglobulin hom-I sau.Nws khi ob qho tib si insulin zoo li kev loj hlob yam tshwm sim (IGFs) I thiab II thiab ncig hauv cov ntshav.Kev sib txuas ntawm cov protein no ua kom ntev ib nrab ntawm lub neej ntawm IGFs thiab hloov pauv lawv cov kev cuam tshuam nrog cov cell nto receptors.
Pair pom zoo | CLIA (Capture-Detection): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
Purity | > 95% raws li kev txiav txim los ntawm SDS-PAGE. |
Buffer Formulation | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH 7.4 |
Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20 ℃ to -80 ℃ thaum tau txais. Pom zoo kom aliquot cov protein rau hauv me me kom pom kev cia. |
Bioantibody | Clinically Diagnosed Case | Tag nrho | |
Qhov zoo | Tsis zoo | ||
Qhov zoo | 35 | 0 | 35 |
Tsis zoo | 1 | 87 | 88 |
Tag nrho | 36 | 87 | 123 |
Qhov tshwj xeeb | 100% | ||
rhiab heev | 97% |
Khoom npe | Cat.Tsis muaj | Clone ID |
IGFBP-1 | AB 0028-1 | 4 H6-2 |
AB 0028-2 | 4C2-3 | |
AB 0028-3 | 2 H11-1 | |
AB 0028-4 | 3 G12-11 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
1. Rutanen EM.Insulin-zoo li kev loj hlob zoo li kev khi cov protein 1: US 1996.
2.Harman, S, Mitchell, et al.Cov Ntshav Qab Zib Cov Ntshav Qab Zib Zoo Li Kev Loj Hlob Kuv (IGF-I), IGF-II, IGF-Binding Protein-3, thiab Prostate-Specific Antigen raws li cov kws kho mob ntawm Cancer Prostate [J].Phau ntawv Journal of Clinical Endocrinology & Metabolism, 2000.