Anti-tib neeg Her2 Antibody, Mouse Monoclonal
Cov ntsiab lus ntawm cov khoom
Cov ntaub ntawv dav dav
Human epidermal growth factor receptor 2 (HER2), tseem hu ua ErbB2, NEU, thiab CD340, yog hom I membrane glycoprotein thiab belongs rau tsev neeg epidermal growth factor (EGF) receptor.HER2 protein tsis tuaj yeem khi txoj kev loj hlob vim qhov tsis muaj ligand binding domain ntawm nws tus kheej thiab autoinhibited constitutively.Txawm li cas los xij, HER2 tsim cov heterodimer nrog lwm cov ligand-bound EGF receptor cov neeg hauv tsev neeg, yog li ruaj khov ligand khi thiab txhim kho kinase-mediated activation ntawm downstream molecules.HER2 ua lub luag haujlwm tseem ceeb hauv kev loj hlob, kev loj hlob ntawm tes thiab kev sib txawv.HER2 noob tau raug tshaj tawm tias muaj kev cuam tshuam nrog kev mob qog noj ntshav thiab tsis zoo nyob rau hauv ntau cov carcinomas, suav nrog lub mis, prostate, zes qe menyuam, mob ntsws thiab lwm yam.
Cov khoom
| Pair pom zoo | CLIA (Capture-Detection): 14-2-15-6 : kuv 15-6-2-10 |
| Purity | > 95%, txiav txim los ntawm SDS-PAGE |
| Buffer Formulation | PBS, pH 7.4. |
| Cia | Khaws nws nyob rau hauv cov xwm txheej tsis muaj menyuam ntawm -20 ℃ to -80 ℃ thaum tau txais. Pom zoo kom aliquot cov protein rau hauv me me kom pom kev cia. |
Cov ntaub ntawv xaj
| Khoom npe | Cat.Tsis muaj | Clone ID |
| Nws 2 | AB 0078-1 | 14-2 |
| AB 0078-2 | 15-6 | |
| AB 0078-3 | 2-10 |
Lus Cim: Bioantibody tuaj yeem kho qhov ntau npaum li koj xav tau.
Citations
1.Krawczyk N, et al.(2009) HER2 xwm txheej ntawm cov qog nqaij hlav tsis tu ncua tom qab kev kho mob ntxiv yuav txawv ntawm qhov pib HER2 ntawm thawj qog.Anticancer Res.29(10): 4019-24.
